YOUR TRUSTED LEADER IN BIOACTIVES

ENDOSEQUENCE BIOACTIVES

A complete line of bioactive materials to cover all of your endodontic material needs.

Brasseler’s complete line of bioactive materials has been thoughtfully developed to cover all of your endodontic material needs while providing you with the best healing and handling characteristics. From our time tested BC Sealer to the latest addition BC Temp, our full line of bioactives can provide the solution you need.  

Prior to reviewing the products, it is helpful to understand the difference between pure bioceramic materials and bioactive materials.

▸  Bioactive Materials Overview
▸  Bioceramic Materials Overview

Bioactives are generally categorized as any product that elicits a positive biological response. In dentistry, the response is typically realized in the form of a release of beneficial calcium, phosphate, or fluoride ions. Bioactives can include non-bioceramic components, as they are defined by what they are designed to do and not by their composition.

Bioceramics are different in that they are defined by both their composition and what they are designed to do. Bioceramics are essentially any inorganic, ceramic material (refractory polycrystalline compounds) used in medicine and dentistry. Brasseler’s bioceramics are pure calcium silicate, calcium phosphate-based bioceramics, which are designed to set hard in the presence of the moisture naturally present in dentin. It is important to note that according to these definitions, products consisting of metals and/or resins are not pure bioceramics.

Finally a material that is biocompatible, anti-inflammatory and antibacterial with no post-operative complications. The feedback from many of my Endodontic Colleagues is amazingly positive.

Dr. Richard Herman

Diplomate of the American Board of Endodontics

Endosequence Root Repair Material’s favorable properties, coupled with it’s ingenious moisture initiated setting reaction and efficient clinical application, represents a step forward in root repair and surgical retrofilling materials.

Dr. Allen Ali Nasseh

Microsurgical Endodontics, Boston, MA

In all my years of viewing high magnification SEMs, I have never seen a sealer form such a consistently intimate bond with dentin.

Dr. Martin Trope

Clinical Professor, University of Pennsylvania

Product Line

EndoSequence BC Sealer

Application: Sealer (optimized for cold hydraulic condensation)

Unlike conventional base/catalyst sealers, BC Sealer™ utilizes the moisture naturally present in the dentinal tubules to initiate its setting reaction. This highly radiopaque and Hydrophilic sealer forms hydroxyapatite upon setting and chemically bonds to both dentin and to our bioceramic points (EndoSequence® BC Points™). BC Sealer is anti-bacterial during setting due to its highly alakaline pH and unlike traditional sealers, BC Sealer exhibits absolutely zero shrinkage!

▸  Watch the Video
▸  Download the Brochure

U.S. Patent Nos.: 7,553,362, 7,575,628, 8,343,271, 8,475,811
European Patent Nos.: 1861341 A4, 2142225 B1

RESEARCH BIBLIOGRAPHY

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EndoSequence BC Sealer
EndoSequence BC Sealer HiFlow

EndoSequence BC Sealer HiFlow

Application: Sealer (optimized for warm obturation)

BC Sealer HiFlow is optimized for warm obturation techniques. Unlike conventional base/catalyst sealers, BC Sealer™ utilizes the moisture naturally present in the dentinal tubules to initiate its setting reaction. This highly radiopaque and Hydrophilic sealer forms hydroxyapatite upon setting and chemically bonds to both dentin and to our bioceramic points (EndoSequence® BC Points™). BC Sealer is anti-bacterial during setting due to its highly alakaline pH and unlike traditional sealers, BC Sealer exhibits absolutely zero shrinkage!

▸  Watch the Video

U.S. Patent Nos.: 7,553,362, 7,575,628, 8,343,271, 8,475,811
European Patent Nos.: 1861341 A4, 2142225 B1

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EndoSequence BC RRM

Application: Perf repair, pulp capping, retrograde fill, apexification

EndoSequence Root Repair Material provides superior handling and healing properties for all of your root repair needs. This highly radiopaque and hydrophilic material has a very small particle size and unique composition that allows it to bond to dentin. It utilizes the moisture naturally present in the dentin to initiate and complete its setting reaction, and it is antibacterial during setting due to its highly alkaline pH.

▸  Watch the Video

U.S. Patent Nos.: 7,553,362, 7,575,628, 8,343,271, 8,475,811
European Patent Nos.: 1861341 A4, 2142225 B1

RESEARCH BIBLIOGRAPHY

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EndoSequence BC RRM
EndoSequence BC RRM Putty

EndoSequence BC RRM Putty

Application: Perf repair, pulp capping, retrograde fill, apexification

A condensable putty consistency available in either a syringe or jar. EndoSequence Root Repair Material provides superior healing properties for all of your root repair needs. This highly radiopaque and hydrophilic material has a very small particle size and unique composition that allows it to bond to dentin. It utilizes the moisture naturally present in the dentin to initiate and complete its setting reaction, and it is antibacterial during setting due to its highly alkaline pH.

▸  Watch the Video

U.S. Patent Nos.: 7,553,362, 7,575,628, 8,343,271, 8,475,811
European Patent Nos.: 1861341 A4, 2142225 B1

RESEARCH BIBLIOGRAPHY

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EndoSequence BC Temp

Application: Intracanal dressing

BC Temp is a premixed bioceramic paste for intracanal dressing. Unlike traditional Calcium Hydroxide pastes, the primary components of BC Temp are Calcium Silicates and Calcium Oxide which combine with the water naturally present in dentin to produce Calcium Hydroxide which dissociates into Ca2 + and OH-. The hydroxyl ions (OH-) released are responsible for a significant increase in the pH of the surrounding tissues, making the environment unsuitable for bacterial growth. The hydration reaction of Calcium Silicates allows BC Temp to have a gradual and slow release of calcium and hydroxyl ions which eliminates the need for frequent applications.

▸  Watch the Video

PRODUCT FAQS

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EndoSequence BC Temp
EndoSequence BC Liner

EndoSequence BC Liner

Application: Orifice barriers, base/liner, indirect pulp capping

EndoSequence BC Liner is a next-generation bioactive hybrid resin optimized for use with BC Sealer and BC RRM. This versatile and durable material chemically bonds to dentin without the need for a bonding agent. The unique, moisture-friendly chemistry seals teeth against bacterial leakage and continuously releases and recharges calcium, phosphate and fluoride ions for a lasting biological benefit. Also avialable in blue for orifice barriers.

▸  Watch the Video
▸  Download the Brochure

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Educational Resources

Bioceramics - Promising New Frontier or Wild West

CE Webinar | Presenters: Dr. JIANING He and Dr. Ali Nasseh

The presenters will review the research and clinical support for the use of bioceramics in endodontics and discuss what we know and what we don’t know about the different materials currently available on the market. 

From Vital Pulp Therapy to Anatomically Directed Root Treatment - Everything is Changing

CE Webinar | Presenter: Dr. Martin Trope

This CE webinar will cover how bioceramic materials have changed our definition of irreversible pulpitis and also how we think about single cone hyraulic obturation techniques.

The Role of Bioactive Materials in Vital Pulp Therapy

CE Webinar | Presenter: Dr. Martin Trope

In this CE webinar, Dr. Martin Trope will suggest new recommendations for vital pulp therapy and discuss the properties of these new materials that have allowed us to expand the role of vital pulp therapy.

Vital Pulp Cryotherapy

CE Webinar | Presenter: Dr. James Bahcall

This CE webinar will cover clinical case selection, treatment and prognosis, through the understanding of proper diagnosis, materials and biological considerations, when performing vital pulp cryotherapy treatment.

The Use of Bioceramics in Endodontics

Podcast | Host: Dr. Phil Klein

Dental podcast hosted by Dr. Phil Klein: This Viva Podcast will discuss the use of bioceramics in endodontics. Our guest is Dr. Ali Nasseh, CEO of Real World Endo and founder of MicroSurgical Endodontics (MSEndo), and a practicing endodontist in Boston, MA.

Bioceramics use in Non-Surgical Root Canal Therapy

Podcast | Host: Dr. Phil Klein

Dental podcast hosted by Dr. Phil Klein: This Viva Podcast will discuss bioceramics use, techniques and indications in non-surgical root canal therapy. Our guest is Dr. Ali Nasseh, CEO of Real World Endo and founder of MicroSurgical Endodontics (MSEndo), and a practicing endodontist in Boston, MA.

Bioceramic use in Surgical Endodontics

Podcast | Host: Dr. Phil Klein

Dental podcast hosted by Dr. Phil Klein: This Viva Podcast will discuss bioceramics use and indications in surgical endodontics. Our guest is Dr. Ali Nasseh, CEO of Real World Endo and founder of MicroSurgical Endodontics (MSEndo), and a practicing endodontist in Boston, MA.

Bioactive Restorative Materials in Endodontics

Podcast | Host: Dr. Phil Klein

Dental podcast hosted by Dr. Phil Klein: This Viva Podcast will discuss bioactive restorative materials in endodontics. Our guest is Dr. Ali Nasseh, CEO of Real World Endo and founder of MicroSurgical Endodontics (MSEndo), and a practicing endodontist in Boston, MA.

Ready to upgrade to EndoSequence Bioctives?